Publications
Publications
50 papers, 2026 back to 2010.
For a more complete list of publications by Prof. Alicia Izquierdo, see ORCID
- 2026
Aguirre CG*, Woo JH*, Alhabbal L, Fujioka T, Moore R, Ye T, Castrellon JJ, Soltani A, Izquierdo A. Sex differences in task engagement and lapse rate during reward learning, Oxford Open Neuroscience 5 kvag004 https://doi.org/10.1093/oons/kvag004. *co-first authors
- 2026
Hoang IB, Munier JJ, Verghese A, Taira M, Abiero A, Leake J, Dawson A, Wilcher M, Ganesan K, Ortega ME*, Reyes V, Greer Z, Millard SJ, DiFazio LE, Sercander C, Bagley E, Winters B, Izquierdo A, Sharpe MJ. Methamphetamine potentiates the use of outcome-specific associations via a hypothalamic-dopamine circuit. Neuron in press.
- 2025
A progressive ratio task with costly resets reveals adaptive effort-delay tradeoffs.
Rivera ZMG, Guerrero Leon K, Cervera M, Aguayo B, Izquierdo A, Wikenheiser AM (2025).
eNeuro 12(11) ENEURO.0258-25.2025.
- 2025
Neural coding of choice and outcome are modulated by uncertainty in orbitofrontal but not secondary motor cortex.
Romero-Sosa JL, Wikenheiser AM, Blair HT, Izquierdo A (2024).
Nat Commun 16 (8931) https://doi.org/10.1038/s41467-025-63866-5.
- 2025
A common stay-on-goal mechanism in anterior cingulate cortex for information and effort choices.
González VV, Malvaez M, Yeghikian A, Wissing S, Sharpe M, Wassum KM, Izquierdo A (2024).
eNeuro 12 (3) ENEURO.0454-24.2025.
- 2025
Examining the effects of varenicline and naltrexone on delay discounting among individuals with alcohol use disorder.
Nieto SJ, MacKillop J, Baskerville WA, Kady A, Izquierdo A, Ray LA (2025).
Alcohol Alcohol 60(6): agaf060.
- 2024
A special role for anterior cingulate cortex, but not orbitofrontal cortex or basolateral amygdala, in choices involving information.
González VV, Zhang Y, Ashikyan SA, Rickard A, Yassine I, Romero-Sosa JL, Blaisdell AP, Izquierdo A (2024).
Cerebral Cortex 34(4): bhae135.
- 2024
Dissociable contributions of basolateral amygdala and ventrolateral orbitofrontal cortex to flexible learning under uncertainty.
Aguirre CG, Woo JH, Romero-Sosa JL, Rivera ZM, Tejada AN, Munier JJ, Perez J, Goldfarb M, Das K, Gomez M, Ye T, Pannu J, Evans K, O’Neill PR, Spigelman I, Soltani A, Izquierdo A (2024).
The Journal of Neuroscience 44(2): e0622232023.
- 2024
Evolutionary Perspectives: Homologies and Analogies.
Weiner KS, Balleine B, Halassa MM, Izquierdo A, Palomero-Gallagher N, Rudebeck PH, Smaers JB, Robbins TW (2024).
In: The Frontal Cortex: Organization, Networks, and Function, edited by M. T. Banich, S. N. Haber, and T. W. Robbins. Strüngmann Forum Reports, vol. 35, J. R. Lupp, series editor. Cambridge, MA: MIT Press, in press.
- 2024
A cross-species analysis of prefrontal cortex homology based on anatomical connectivity, behavior, and cell types.
Izquierdo A (2024).
In: The Frontal Cortex: Organization, Networks, and Function, edited by M. T. Banich, S. N. Haber, and T. W. Robbins. Strüngmann Forum Reports, vol. 35, J. R. Lupp, series editor. Cambridge, MA: MIT Press, in press.
- 2023
Theta oscillations in anterior cingulate cortex and orbitofrontal cortex differentially modulate accuracy and speed in flexible reward learning.
Ye T, Romero-Sosa JL, Rickard A, Aguirre CG, Wikenheiser AM, Blair HT, Izquierdo A (2023).
Oxford Open Neuroscience 2: kvad005.
- 2023
Mechanisms of adjustments to different types of uncertainty in the reward environment across mice and monkeys.
Woo JH, Aguirre CG, Bari BA, Tsutsui K, Grabenhorst F, Cohen JY, Schultz W, Izquierdo A, Soltani A (2023).
Cognitive, Affective and Behavioral Neuroscience 23(3): 600-619.
- 2023
Information value in paradoxical choice.
González VV, Izquierdo A, Blaisdell A (2023).
Comparative Cognition & Behavior Reviews 18: 011-031.
- 2023
A hardware system for real-time decoding of in vivo calcium imaging data.
Chen Z, Blair GJ, Guo C, Zhou J, Romero-Sosa JL, Izquierdo A, Golshani P, Cong J, Aharoni D, Blair HT (2023).
eLife 12:e78344.
- 2022
Foraging with the frontal cortex: A cross-species evaluation of reward-guided behavior.
Rudebeck PH and Izquierdo A (2022).
Neuropsychopharmacology 47: 134–146.
- 2021
Translational opportunities in animal and human models to study alcohol use disorder.
Nieto SJ, Grodin EN, Aguirre C, Izquierdo A, Ray LA (2021).
Translational Psychiatry in press.
- 2021
The Orbitofrontal Cortex in Temporal Cognition.
Romero Sosa, JL, Buonomano D, Izquierdo A (2021).
Behavioral Neuroscience 135(2): 154-164.
- 2021
Unique features of stimulus-based probabilistic reversal learning.
Harris C*, Aguirre CG*, Kolli S, Das K, Izquierdo A#, Soltani A# (2021).
Behavioral Neuroscience 135(4):550-570. *co-first authors #co-senior authors
- 2021
Touchscreen response technology and the power of stimulus-based approaches in freely behaving animals.
Izquierdo A (2021).
Genes Brain Behav 20(1): e12720. doi: 10.1111/gbb.12720.
- 2020
Sex-dependent effects of chronic intermittent voluntary alcohol consumption on attentional, not motivational, measures during probabilistic learning and reversal.
Aguirre CG, Stolyarova A, Das K, Kolli S, Marty V, Ray L, Spigelman I, Izquierdo A (2020).
PLoSONE 15(6): e0234729.
- 2020
Chemogenetic modulation and single-photon calcium imaging in anterior cingulate cortex reveal a mechanism for effort-based decisions.
Hart EE*, Blair GJ*, O’Dell TJ, Blair HT, Izquierdo A (2020).
The Journal of Neuroscience 40 (29) 5628-5643. *co-first authors
- 2019
Contributions of anterior cingulate cortex and basolateral amygdala to decision confidence and learning under uncertainty.
Stolyarova A*, Rakhshan M*, Hart EE, O’Dell TJ, Peters MAK, Lau H, Soltani A, Izquierdo A (2019).
Nature Communications 10: 4704. *co-first authors
- 2019
Adaptive learning under expected and unexpected uncertainty.
Soltani A and Izquierdo A (2019).
Nat Rev Neurosci doi: 10.1038/s41583-019-0180-y.
- 2019
Quantity versus quality: Convergent findings in effort-based choice tasks.
Hart EE and Izquierdo A (2019).
Behavioural Processes 164: 178-185.
- 2019
Animal models of adaptive learning and decision making.
Izquierdo A, Aguirre C, Hart EE, Stolyarova A (2019).
Psychiatric Disorders (2nd Edition) Methods Mol Biol 2011:105-119.
- 2018
Persistent effect of withdrawal from intravenous methamphetamine self-administration on brain activation and behavioral economic indices involving an effort cost.
Hart EE, Gerson JO, Izquierdo A (2018).
Neuropharmacology 140: 130-138.
- 2017
Functional heterogeneity within rat orbitofrontal cortex in reward learning and decision making.
Izquierdo (2017).
The Journal of Neuroscience 37(44): 10529-10540.
- 2017
Complementary contributions of basolateral amygdala and orbitofrontal cortex to value learning under uncertainty.
Stolyarova A and Izquierdo A (2017).
eLife https://elifesciences.org/articles/27483.
- 2017
Steep effort discounting of a preferred reward over a freely-available option in prolonged methamphetamine withdrawal in male rats.
Thompson AB, Gerson J, Stolyarova A, Bugarin A, Hart EE, Jentsch JD, Izquierdo A (2017).
Psychopharmacology 234(18): 2697-2705.
- 2017
Anterior cingulate cortex supports effort allocation toward a qualitatively preferred option.
Hart EE, Gerson JO, Zoken Y, Garcia M, and Izquierdo A (2017).
Eur J Neurosci 46(1): 1682-1688.
- 2017
Basolateral amygdala supports the maintenance of value and effortful choice of a preferred option.
Hart EE and Izquierdo A (2017).
Eur J Neurosci 45(3): 388-397.
- 2017
Rigid patterns of effortful choice behavior after acute stress in rats.
Hart EE, Stolyarova A, Conoscenti M, Minor TR, Izquierdo A (2017).
Stress 20(1): 19-28.
- 2016
Sex differences, learning flexibility, and striatal D1 and D2 following adolescent drug exposure in rats.
Izquierdo A, Pozos H, De La Torre A, DeShields S, Cevallos J, Rodriguez J, Stolyarova A (2016).
Behavioural Brain Research 308: 104-14.
- 2016
The neural basis of reversal learning: An updated perspective.
Izquierdo A, Radke AK, Brigman JL, Rudebeck PH, Holmes A (2016).
Neuroscience doi: 10.1016/j.neuroscience.2016.03.021.
- 2016
Hijacking translation in addiction.
Izquierdo A and Silva AJ (2016).
eLife doi: 10.7554/eLife.14576.
- 2015
The basolateral amygdala in reward learning and addiction.
Wassum KM & Izquierdo A (2015).
Neuroscience and Biobehavioral Reviews 57: 271-283.
- 2015
Methamphetamine blocks exercise-induced increases in Bdnf and Drd2 gene expression in frontal cortex and striatum.
Thompson AB, Stolyarova A, Ying Z, Zhuang Y, Gómez-Pinilla F, Izquierdo A (2015).
Neuropharmacology 99: 658-664.
- 2015
Distinct patterns of reward valuation and amygdala-prefrontal cortex synaptic remodeling in adolescence and adulthood.
Stolyarova A and Izquierdo A (2015).
Frontiers in Behavioral Neuroscience doi: 10.3389/fnbeh.2015.00115.
- 2015
Post-training depletions of basolateral amygdala serotonin fail to disrupt discrimination, retention, or reversal learning.
Ochoa JG, Stolyarova A, Kaur A, Hart EE, Bugarin A, Izquierdo A (2015).
Frontiers in Neurosciencedoi: 10.3389/fnins.2015.00155.
- 2015
Reductions in frontocortical cytokine levels are associated with long-lasting alterations in reward valuation after methamphetamine.
Stolyarova A, Thompson AB, Barrientos RM, Izquierdo A (2015).
Neuropsychopharmacology 40: 1234-1242.
- 2014
Responses to positive and negative feedback and associated dopamine and serotonin transporter binding after methamphetamine.
Stolyarova A, O’Dell SJ, Marshall JF, Izquierdo A (2014).
Behavioural Brain Research 271: 195-202.
- 2014
Long-term effects of exposure to methamphetamine in adolescent rats.
Ye T, Pozos H, Phillips TJ, Izquierdo A (2014).
Drug and Alcohol Dependence 138: 17-23.
- 2013
Basolateral amygdala lesions facilitate reward choices after negative feedback in rats.
Izquierdo A, Darling C, Manos N, Pozos H, Kim C, Ostrander S, Cazares V, Stepp H, Rudebeck PH (2013).
The Journal of Neuroscience 33(9): 4105-9.
- 2012
Comparison of single-dose and escalating methamphetamine administration on reversal learning in rats.
Kosheleff AR, Rodriguez D, O’Dell SJ, Marshall JF, Izquierdo A (2012).
Psychopharmacology, 224(3):459-67.
- 2012
Impaired reward learning and intact motivation after serotonin depletion in rats.
Izquierdo A, Carlos K, Ostrander S, Rodriguez D, McCall-Craddolph A, Yagnik G, Zhou F (2012).
Behavioural Brain Research, 233 (2): 494-9.
- 2012
Reversal learning as a measure of impulsive and compulsive behavior in addictions.
Izquierdo A and Jentsch JD (2012).
In: Robbins, TW (Ed.) Impulsivity and Compulsivity. Psychopharmacology special issue, 219 (2): 607-20
- 2012
Rodent models of adaptive decision making.
Izquierdo A and Belcher AM (2012).
In: Kobeissy FH (Ed.) Psychiatric Disorders: Methods Mol Biol, Humana Press, New York, 829: 85-101.
- 2012
Work aversion and associated changes in dopamine and serotonin transporter after methamphetamine exposure in rats.
Kosheleff AR, Grimes M, O’Dell SJ, Marshall JF, Izquierdo A. (2012).
Psychopharmacology, 219(2): 411-20.
- 2011
Orbitofrontal cortex and basolateral amygdala lesions result in suboptimal and dissociable reward choices on cue-guided effort in rats.
Ostrander S, Cazares VA, Kim C, Cheung S, Gonzalez I, Izquierdo A. (2011).
In: Baxter, MG (Ed.), Translating Models in Prefrontal Cortex Function between Animals and Humans. Behavioral Neuroscience, 125(3): 350-359.
- 2010
Reversal-specific learning impairments following a binge regimen of methamphetamine in rats: Possible involvement of striatal dopamine.
Izquierdo A, Belcher AM, Scott L, Cazares VA, Chen J, O’Dell SJ, Malvaez M, Wu T, and Marshall JF (2010)
Neuropsychopharmacology 35: 505-514.
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